Jump to content

Johnson & Johnson scraps Alzheimer's trials on safety concerns - General Hangout & Discussions - InviteHawk - Your Only Source for Free Torrent Invites

Buy, Sell, Trade or Find Free Torrent Invites for Private Torrent Trackers Such As redacted, blutopia, losslessclub, femdomcult, filelist, Chdbits, Uhdbits, empornium, iptorrents, hdbits, gazellegames, animebytes, privatehd, myspleen, torrentleech, morethantv, bibliotik, alpharatio, blady, passthepopcorn, brokenstones, pornbay, cgpeers, cinemageddon, broadcasthenet, learnbits, torrentseeds, beyondhd, cinemaz, u2.dmhy, Karagarga, PTerclub, Nyaa.si, Polishtracker etc.

Johnson & Johnson scraps Alzheimer's trials on safety concerns

Recommended Posts

Johnson and Johnson said it would stop mid-stage trials testing its experimental Alzheimer's drug after observing safety issues, the latest drugmaker to abandon developing treatments for the memory-robbing disease.

Some trial participants showed serious elevations of liver enzymes and the company concluded that the benefit-risk ratio offered by the drug, atabecestat, no longer supported its development, said Janssen, a unit of Johnson and Johnson.

Atabecestat belongs to a class of experimental Alzheimer's drugs called BACE inhibitors that block an enzyme involved in the production of a protein that creates brain plaques, which are considered a major cause for the disease.

Analysts expect the successful development of a treatment for the disease, which affects about 5.7 million Americans, to virtually guarantee multi-billion dollar annual sales.

However, several drugmakers, including Pfizer and Merck, have been forced to abandon trials over lack of effectiveness or safety concerns.

Eli Lilly & Co and AstraZeneca Plc are testing their BACE inhibitor, lanabecestat, in late-stage trials and are due to report results next year.

Johnson & Johnson was testing atabecestat to slow cognitive decline in certain patients identified to be progressing to Alzheimer's dementia.

Link to comment
Share on other sites

This topic is now closed to further replies.
  • Customer Reviews

  • Create New...

Important Information

By using this site, you agree to our Terms of Use.